A sore throat can usually be seen as a symptom of an acute upper respiratory tract infection and can be viral or bacterial. It is a usually a self limiting condition and should usually resolve in one week.  It may occur alone or with other symptoms such as cough, runny nose or a headache.

Cuases 
  • Viral or bacterial infection 
  • Laryngitis 

  • GORD
  • Physical obstruction 
  • Chemical irritation
  • Medication related for example a medication-induced blood dyscrasias as a result of carbimazole


COVID-19

Consider the possibility of COVID-19 and ensure that the patient tests for the virus and isolates if possible 

Differential Diagnosis 

Glandular Fever:

  • Infectious mononucleosis (glandular fever) is a cause of viral sore throat, especially in adolescents or young adults
  • Epstein-Barr virus causes the condition, which may result in up to six months of malaise- routine referral required 


Quinsy

  • Tonsillar abscess, requiring drainage and antibiotic treatment.
  • The patient will present with a temperature and maybe unwell with one tonsil that is usually tense and enlarged-Immediate referral is necessary.


Blood dyscrasias 

  • For example neutropenia and agranulocytosis present as a result of bone marrow suppression that maybe due to medication i.e. Carbimazole-  Urgent referral is necessary


Referral Criteria 

Call 999:

  • If physically unable to swallow fluids with or without excessive drooling
  • Meningeal symptoms and rash Anaphylactic symptoms
  • Swallowed or inhaled foreign object

GP referral needed if:

  • Presented with dysphagia (difficulty in swallowing fluids and own saliva)
  • Suspected Quinsy
  • Potential medication-induced blood dyscrasias e.g. carbimazole (BNF carries this warning- very important)

Routine GP referral: 

  • Bacterial Infection – yellow/green pus, has a fever and swollen neck for more than 3 days
  • Worsening symptoms > 3 days with OTC treatment*
  • Glandular fever




Pharmacological Treatments

Oral Analgesic

SIGN recommends paracetamol as first-line choice and notes that NSAIDs are not routinely recommended.

See Paracetamol and Ibuprofen for more information (Click below)
 

Local anaesthetics,

Benzocaine and lidocaine, are contained in aerosol sprays or throat lozenges for example Difflam spray 

Licensing: Difflam oral rinse over 12 years old 

Local antiseptics,

Such as benzalkonium chloride and hexylresorcinol, are contained in throat lozenges

Glycerin, honey and lemon preparations are also available. These are useful demulcents which give short-term relief.

Pregnancy and breastfeeding: Safe