Pre-Reg Questions

Gastrointestinal

Which of the following is not considered to be a risk factor of proton pump inhibitors?

  1. Risk of gastric cancer
  2. Risk of gastrointestinal infection
  3. Risk of fractures
  4. Risk of esophagitis
  5. Risk of osteoporosis

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4. Risk of esophagitis

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Respiratory

A patient during his admission complains that he has had a sore mouth for several weeks.

Which of the following drugs is the most likely cause of his sore mouth?

  1. aspirin
  2. isosorbide mononitrate
  3. ramipril
  4. Relvar Ellipta
  5. salbutamol

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  1. Relvar Ellipta

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What dose of prednisolone should be used for acute exacerbations of COPD?

  1. 10 mg daily for 5 days
  2. 20 mg daily for 5 days
  3. 30mg daily for 5 days
  4. 40mg daily for 5 days
  5. 40 mg daily for 7 days

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  1. 30mg daily for 5 days

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What plasma-theophylline concentration is required for satisfactory bronchodilation in most individuals?

1. 0.1 – 0.2 mg/L
2. 1–2mg/L
3. 10 – 20 micromol/L
4. 10 – 20 mg/L
5. 55 – 110 mg/L

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  1. 10-20mg/L

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Cardiovascular

A 76-year-old man is taking the following medicines:

  • atorvastatin 40 mg once daily
  • dipyridamole m/r 200 mg twice daily
  • omeprazole 20 mg once daily
  • metformin m/r 500 mg three times daily
  • ramipril 5mg once daily

He has type 2 diabetes and had a transient ischaemic attack two years ago. He has just been diagnosed with AF and is to commence rivaroxaban 20 mg once daily.

Which of his existing medicines should be stopped due to the commencement of rivaroxaban?

  1. atorvastatin
  2. dipyridamole
  3. esomeprazole
  4. metformin
  5. ramipril

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  1. dipyridamole

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Infections

Mr AB is diagnosed with a simple UTI in community. Which is the best treatment option for Mr AB?

1. Co-amoxiclav
2. Gentamicin
3. Nitrofurantoin
4. Teicoplanin
5. Trimethoprim

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  1. Nitrofurantoin

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Endocrine

A 62-year-old woman has started to take pioglitazone 30 mg once daily 4 weeks ago. She has also been taking metformin 500mg three times a day for the past three years. When collecting her repeat prescription, she complains that she’s recently been having dark urine, nausea and fatigue for the last two weeks.

What is the most appropriate advice to give to this patient?

  1. She is experiencing a side-effect of pioglitazone, and whilst safe to continue taking it, she may wish to see her GP for an alternative
  2. She should see her GP as the dose of pioglitazone may need to be reduced
  3. She should see her GP as the dose of pioglitazone may need to be increased
  4. Stop taking pioglitazone straight away and see her GP as soon as possible
  5. The symptoms described are not known to be caused by pioglitazone

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  1. Stop taking pioglitazone straight away and see her GP as soon as possible

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A patient with type 2 diabetes needs to commence insulin treatment and would like to use an insulin preparation that is injected subcutaneously twice daily with meals.

Which of the following is the most suitable insulin preparation for this regimen?

  1. Actrapid (soluble insulin)
  2. Apidra (insulin glulisine)
  3. Humalog Mix25 (biphasic insulin lispro)
  4. Lantus (insulin glargine)
  5. NovoRapid (insulin aspart)

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  1. Humalog Mix25 (biphasic insulin lispro)

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Central Nervous System

What is the danger with stopping Mr AB’s Parkinson’s disease medications abruptly?

  1. Confusion
  2. Neuroleptic Malignant Syndrome
  3. Side effects
  4. Steven-Johnsons Syndrome
  5. Worsening symtoms

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  1. Neuroleptic Malignant Syndrome

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Musculoskeletal

  1. A 68-year-old man has an acute attack of gout. He had an MI three years ago and has mild osteoarthritis but is otherwise well. He is taking the following medication:

• aspirin 75 mg once daily
• simvastatin 40mg mg once daily
• ramipril 5 mg once daily
• co-codamol 30/500 mg two tablets up to four times a day as required

He also has a penicillin allergy

What is the most suitable drug treatment for his acute attack of gout?

  1. allopurinol
  2. colchicine
  3. diclofenac sodium
  4. etoricoxib
  5. febuxostat

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  1. Colchicine

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OTC

In which of the following cases would you NOT be able to sell the OTC product to the patient?

  1. 21-year-old patient asking for chloramphenicol who had laser eye surgery 9 months ago
  2. 26-year-old female with an irregular cycle asking for tranexamic acid
  3. 50-year-old male patient asking for tamsulosin who has had the symptoms for four months
  4. 59-year-old female asking for clotrimazole 2% cream and has a white, cottage cheese vaginal discharge
  5. 63-year-old male patient asking for sumatriptan who smokes 10 cigarettes daily

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  1. 26-year-old female with an irregular cycle asking for tranexamic acid

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MEP

A 45-year-old man presents his prescription for zomorph 10 mg m/r tablets.

What is the maximum recommended duration of supply on a single prescription for this medicine?

  1.  7 days
  2. 28 days
  3. 30 days
  4. 3 months
  5. 6 months

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  1. 30 days

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You want to obtain guidance on the record keeping requirements for the management and monitoring of vaccine stocks in a pharmacy.

Which of the following is the most appropriate reference source to consult for this information?

  1. British National Formulary
  2.  British Pharmacopoeia
  3.  Immunisation against infectious disease (known as the Green Book)
  4.  Martindale: The Complete Drug Reference
  5.  Rules and Guidance for Pharmaceutical Manufacturers and Distributors (known as the Orange Guide)

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  1. Immunisation against infectious disease (known as the Green Book)

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You are to take on the role of the Responsible Pharmacist in the pharmacy you will be working in.

What is the minimum period of time that the pharmacy record has to be kept?

  1. 1 year
  2. 2 years
  3. 5 years
  4. 7 years
  5. 10 years

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  1. 5 years

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Which of the following is NOT a requirement for an emergency supply to be made?

  1. A prescriber must authorise the emergency supply
  2. Cannot supply more than 28 days treatment for POMs
  3. You must question the patient about the requirement
  4. The has been previously prescribed and used by the patient
  5. There must be an immediate need

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  1. A prescriber must authorise the emergency supply

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